The Cardiovascular effects coptis

Berberine has antihypertensive effect. Its decompression mechanism is related to direct dilation of blood vessels, inhibition of vasomotor center, anti-adrenaline, inhibition of pressure rise reflex, anti-cholinesterase and other pathways. Coptis and other alkaloids also have antihypertensive effects. Berberine can stimulate the heart and increase coronary blood flow, can significantly improve the ability of the heart, brain, and body to withstand hypoxia, and significantly reduce myocardial oxygen consumption in normal and depleted hearts. Jatrorrhizine and berbamine can reduce the extent of experimental myocardial infarction and reduce its extent. Berberine and jatrorrhizine can antagonize the effects of adrenaline-induced arrhythmias. Can significantly reduce induced ventricular premature beats, ventricular tachycardia. Jelhorrhizine also has a significant antiarrhythmic effect.