The Digestive system coptis

Coptis and berberine have the effect of activating and inhibiting bidirectional regulation of gastrointestinal smooth muscle. Low concentrations have excitatory effects on smooth muscles and spasmolytic effects at high concentrations. Berberine has antidiarrheal effect and can significantly counteract diarrhea in mice caused by senna and the like. May be related to the elimination of inflammation and elimination of intestinal wall edema. Coptis, berberine and Huanglian Jiedu decoction have significant protective effects on gastric mucosa and can significantly resist experimental ulcers in rats. Berberine has a significant choleretic effect, can promote bile formation and promote the excretion of conjugated bilirubin. The jatrorrhizine also has a beneficial effect on the gall bladder, but it is weaker and longer lasting.